Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep729 | Steroid metabolism + action | ECE2017

Dexras1 regulates MSC-derived adipogenesis and osteogenesis

Seok Jo Woon , Kim Daeun , Lee Hye min , Yoon Bo kyung , Kim Hyo Jung , Kim Jae-woo

Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into various types of cells including chondrocytes, osteoblasts and adipocytes. Since these types of cells are simultaneously derived from the same precursor cell, adipogenesis and osteoblastogenesis are thought to be counter-related. It is well-known that chronic treatment of steroid can induce Cushing’s syndrome which has phenotypes like visceral adiposity and osteoporosis. Cell fate of d...